What are asteroid bodies in sporotrichosis?

What are asteroid bodies in sporotrichosis?

The asteroid body in Sporotrichosis (AB) is a characteristic structure that allows diagnosis in lymphangitic presentations and whose generation and composition is not fully understood. Our study focused on the biological relationship between the yeast and host elements present in the AB.

What is an asteroid body?

Asteroid bodies are stellate acidophilic inclusion bodies, usually 20 to 30 um in size with as many as 30 radiate arms found within the cytoplasm of multinucleated giant cells.

Is sporothrix dimorphic?

Sporothrix schenckii is a dimorphic fungus. In its saprophytic stage or when cultured at 25°C, it assumes a filamentous form, composed of hyaline, septate hyphae 1 to 2 μm wide, with conidiogenous cells arising from undifferentiated hyphae forming conidia in groups on small, clustered denticles.

Can Sporotrichosis be cured?

Most cases of sporotrichosis only involve the skin or the tissues underneath the skin. These infections are not life-threatening, but must be treated with prescription antifungal medicine for several months. The most common treatment for this type of sporotrichosis is itraconazole, taken by mouth for 3 to 6 months.

What does asteroid mean in science?

asteroid, also called minor planet or planetoid, any of a host of small bodies, about 1,000 km (600 miles) or less in diameter, that orbit the Sun primarily between the orbits of Mars and Jupiter in a nearly flat ring called the asteroid belt.

What is the pathogenesis of sporotrichosis?

Pathophysiology. Skin lesions of sporotrichosis appear as red nodular lesions. Microscopically the lesions display central areas of acute infections and peripheral areas of granulomas. In the tissue, the organism appears as a small, budding yeast that is cigar-shaped.

How do you know if you have sporotrichosis?

What are the symptoms of sporotrichosis? The first symptom is a small pink, red or purple painless bump resembling an insect bite. The bump, or lesion, usually appears on the finger, hand or arm where the fungus first entered through a break in the skin.

What are the 3 different types of asteroids?

The three broad composition classes of asteroids are C-, S-, and M-types.

• The C-type (chondrite) asteroids are most common. They probably consist of clay and silicate rocks, and are dark in appearance.
• The S-types (“stony”) are made up of silicate materials and nickel-iron.
• The M-types are metallic (nickel-iron).

What are the chemical composition of an asteroid?

They are made up of oxygen and silicon, the number one and number two most abundant elements in the Earth’s crust. The metallic asteroids are composed of up to 80% iron and 20% a mixture of nickel, iridium, palladium, platinum, gold, magnesium and other precious metals such as osmium, ruthenium and rhodium.

What is the pathophysiology of sporotrichosis?

In sporotrichosis, sections show epidermal hyperplasia overlying a marked acute and chronic inflammatory response (figure 1). Higher power shows the inflammation infiltrates the overlying epidermis (figure 2). The infiltrate is polymorphous with giant cells, histiocytes, and focal neutrophilic microabscess formation (figure 3).

What is the size of the AB in sporotrichosis?

In sporotrichosis, the AB are extracellular eosinophilic structures, 15-35 microm in diameter, and located within abscesses. One to three are found in a section.

What causes sporotrichosis in armadillos?

In Uruguay and more recently in southern Brazil, the hunting of armadillos have been related to cases of sporotrichosis. In some situations, such as in an area of endemicity in Peru, the cat owners, outdoor activities, and low socioeconomic status were identified as risk factors for acquiring sporotrichosis.